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Discover Methyl B Complete™

Methyl B Complete contains five key nutrients that are involved in homocysteine metabolism: Folate as Quatrefolic® for increased bioactivity; Trimethylglycine (TMG); and vitamins B12 (a combination of Methylcobalamin & Adenosylcobalamin), B6, and B2 (Riboflavin).

This unique formula was created to support optimal methylation and help support healthy homocysteine levels already within normal range.

 

Methyl B Complete Features

  • This formula is exceptional for those with defective MTHFR genes. Providing bioactive forms of four essential B-Vitamins together with TMG to synergistically support methylation processes and normal homocysteine metabolism
  • Manufactured in the USA in a NSF/GMP-certified and FDA-inspected facility for guaranteed quality and potency
  • Supports the maintenance of healthy homocysteine levels
  • Supports healthy methylation of estrogen, dopamine, epinephrine, heavy metals, and environmental toxins
  • Supports cardiovascular and neurological health
  • Supports optimal energy production
  • Free of Magnesium Stearate
  • Pharmaceutical grade

𝐏𝐑𝐎𝐔𝐃𝐋𝐘 𝐑𝐄𝐂𝐎𝐌𝐌𝐄𝐍𝐃𝐄𝐃 by Health Practitioners Worldwide.

Safety Information
Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged.

Indications
Optimal Methylation Support Formula

Ingredients
Riboflavin (as riboflavin 5'-phosphate sodium) 25 mg, Vitamin B6 (as pyridoxal 5'-phosphate) 15 mg, Folate [(1,700 mcg DFE as Calcium Folinate and 1,700 mcg DFE as (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)(Quatrefolic®)], Vitamin B12 (500 mcg Adenosylcobalamin & 500 mcg Methylcobalamin) 1000 mcg, TrimethylgIycine (TMG) 650 mg

Other Ingredients
DRcaps® Acid-Resistant Capsule (Vegetable Cellulose), Tricalcium Phosphate.

DOES NOT CONTAIN
Fillers, wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, nuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives.


All Pure TheraPro Rx Formulas Meet or Exceed cGMP Quality Standards. This product is manufactured in the United States in a FDA inspected and NSF / GMP certified facility.

Quatrefolic® is a registered trademark of Gnosis SPA Corp. Produced under US patent 7,947,662.

4.7
Rated 4.7 out of 5 stars
Based on 154 reviews
Total 5 star reviews: 130 Total 4 star reviews: 16 Total 3 star reviews: 3 Total 2 star reviews: 1 Total 1 star reviews: 4
95%would recommend this product
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154 reviews
  • LB Profile picture for Lynnette B.
    Lynnette B.
    I recommend this product
    Rated 5 out of 5 stars
    12 months ago
    Amazing!

    I have struggled with chronic fatigue since I can’t remember. I have been to the doctors and had test run to be told that I had some type of autoimmune issue but nothing concrete. Western medicine did not help and I felt helpless. I decided to look for a more natural way to help with my energy levels. So happy to find a supplement that is full of actual nutrients that my body needs, and can absorb!! Thank you Pure!!

  • CA
    Carol Ann R.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Doctor Recommended

    On the advice of my doctor, I have been taking Pure Therapro Methyl B Complete for many years. It is a high quality supplement and recommended to help with the health issue.

  • EO
    Eva O.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Very Happy with this Methylated vitamin

    I have been purchasing this particular Methylated vitamin only this year, 2024. After a doctor diagnosed my child with homozygous MTHFR C677T in 2020 with strict instructions that she restrict her folate intake to only a methylated version, we started supplementing her with an expensive prescribed methylated folate that our prescription plan did not cover. OTC vitamins didn’t seem to have methylated versions in stores so research led me to look for one containing Quatrefolic version of folate and to look for a methylated B-12. Circa 2023, I decided to look for a multi-vitamin for my own personal health. It was at that time we discovered that our entire family has Folate and B-12 methylation issues due to homo & heterozygous MTHFR and homozygous MTRR. We also have Vitamin D absorption issues. So here we are. I do like that they are 3rd party tested and are manufactured in an FDA certified facility using pharmaceutical grade materials here in the USA.

  • B
    Bran
    Verified Buyer
    I do not recommend this product
    Rated 1 out of 5 stars
    3 months ago
    Weird reactions...

    I finally got around to trying this item for myself after having recommended it to others I know, and even having bought it for a family member in the past (who I just found out had to discontinue using it shortly after starting it). For me I started having heat flashes, my whole body became extremely achy in the joints especially, and I was urinating a lot. The other thing that I'm not sure whether it was related or not, but the symptoms were noticeable after using this B Complex, were a pins and needles sensation in my legs and feet, arms and hands, sometimes my face and head while I was trying to sleep. Obviously this interrupted sleep. The pins and needles symptoms seemed to be there while I was awake but not as bad possibly because I was moving around. As someone with several MTHFR mutations I really wanted this to work, and after my other brand ran out, I decided to finally try this one as I love the concept of the company (pure supplements), but I was brand loyal to another company with my B Complex for years. For me anyway, I'll go back to my other brand as I never had the effects from that B supplement as I had upon starting this one, unfortunately. Again, I think this company is good, but this item did not work for me at all.

  • LM
    Lynn M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    4 months ago
    Good

    I haven’t been taking it long enough to really know whether or not it’s doing anything. But from what I read, I’m looking for good results.

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Frequently Asked Questions

Ingredients
Riboflavin (as riboflavin 5'-phosphate sodium) 25 mg, Vitamin B6 (as pyridoxal 5'-phosphate) 15 mg, Folate [(1,700 mcg DFE as Calcium Folinate and 1,700 mcg DFE as (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)(Quatrefolic®)], Vitamin B12 (500 mcg adenosylcobalamin & 500 mcg methylcobalamin) 1000 mcg, TrimethylgIycine (TMG) 650 mg

Other Ingredients
DRcaps® Acid-Resistant Capsule (Vegetable Cellulose), Tricalcium Phosphate

DOES NOT CONTAIN
Fillers, wheat, gluten, yeast, soy protein, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or artificial preservatives.

**Storage:**
PLEASE NOTE - B vitamins are extremely hygroscopic (absorb moisture from the air). If the desiccant is removed from the bottle and/or the capsules are placed into a pill box / plastic bag, the capsules may start to degrade especially if you are in a hot or humid climate. We recommend storing the bottle or your pill box in the refrigerator during hot / humid months for optimal freshness.

All Pure TheraPro Rx Formulas Meet or Exceed cGMP Quality Standards. This product is manufactured in the USA in a FDA inspected, NSF and GMP-certified facility for guaranteed quality and potency.

Methyl B Complete™ Supports Metabolic Function & Energy

Methyl B Complete™ is a cutting-edge formula comprised of five key nutrients: Quatrefolic® Folate to support the MTHFR genetic pathway and healthy methylation, trimethylglycine, a super-bioactive blend of Vitamin B12 (including patented MecobalActive® Methylcobalamin), as well as Vitamin B6 in its coenzyme form and the highest-quality Vitamin B2 (Riboflavin). This synergistic formula supports healthy homocysteine levels, energy production, detoxification, metabolism, and cognitive function.

Clinically Effective Formula

MTHFR stands for Methylenetetrahydrofolate Reductase, an enzyme that plays a key role in nutrient absorption and detoxification. It is instrumental in the methylation process, which helps regulate metabolic and MTHFR genetic pathways. Some individuals may have genetic variations that affect how certain vitamins, like B12 and folate, are processed. These vitamins are essential for metabolism, energy release from food, detoxification, and nervous system function. Methyl B Complete™ contains pre-methylated nutrients for optimal absorption.


Uncompromising Quality

Formulated with only the highest-quality B vitamins in their most bioavailable forms, Methyl B Complete™ is designed to support those looking for enhanced methylation and nutrient utilization. At PureTheraPro Rx®, we use only the finest patented Quatrefolic® Folate, along with coenzyme and pre-methylated B vitamins for superior absorption and bioavailability.

Purity Is Our Priority

Pure TheraPro Rx® provides supplement solutions to ensure your body gets the micronutrients necessary to support total-body health and vitality. Pure TheraPro Rx® supplements do not contain any fillers such as rice flour, corn starch, or wood pulp fibers like cellulose. Our manufacturing facility adheres to strict NSF/cGMP (Current Good Manufacturing Practices) guidelines.

A comprehensive system

Many of our biological systems are simultaneously impacted by lifestyle, diet and supplementation. When you provide an optimized environment for nutrients, they will work synergistically, resulting in greater outcomes. We recommend several complementary products based on supporting clinical study data and customer feedback.