3rd Party
Lab Tested

Fast Domestic Shipping

Safe & Secure Checkout

Free Shipping Above $75*

Safe & Secure Checkout

3rd Party Lab Tested

Fast Domestic Shipping

180 Day Return Guarantee

Discover Methyl B Complete™

Methyl B Complete contains five key nutrients that are involved in homocysteine metabolism: Folate as Quatrefolic® for increased bioactivity; Trimethylglycine (TMG); and v1itamins B12 (a combination of Methylcobalamin & Adenosylcobalamin), B6, and B2 (Riboflavin).

This unique formula was created to support optimal methylation and help support healthy homocysteine levels already within normal range.

 

Methyl B Complete Features
  • This formula is exceptional for those with defective MTHFR genes. Providing bioactive forms of four essential B-Vitamins together with TMG to synergistically support methylation processes and normal homocysteine metabolism
  • Manufactured in the USA in a NSF/GMP-certified and FDA-inspected facility for guaranteed quality and potency
  • Supports the maintenance of healthy homocysteine levels
  • Supports healthy methylation of estrogen, dopamine, epinephrine, heavy metals, and environmental toxins
  • Supports cardiovascular and neurological health
  • Supports optimal energy production
  • Free of Magnesium Stearate
  • Pharmaceutical grade

𝐏𝐑𝐎𝐔𝐃𝐋𝐘 𝐑𝐄𝐂𝐎𝐌𝐌𝐄𝐍𝐃𝐄𝐃 by Health Practitioners Worldwide.

Safety Information
Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged.

Indications
Optimal Methylation Support Formula

Ingredients
Riboflavin (as riboflavin 5'-phosphate sodium) 25 mg, Vitamin B6 (as pyridoxal 5'-phosphate) 15 mg, Folate [(1,700 mcg DFE as Calcium Folinate and 1,700 mcg DFE as (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)(Quatrefolic®)], Vitamin B12 (500 mcg Adenosylcobalamin & 500 mcg Methylcobalamin) 1000 mcg, TrimethylgIycine (TMG) 650 mg

Other Ingredients
DRcaps® Acid-Resistant Capsule (Vegetable Cellulose), Tricalcium Phosphate.

DOES NOT CONTAIN
Fillers, wheat, gluten, corn protein, yeast, soy, animal or dairy products, fish, shellfish, nuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives.


All Pure TheraPro Rx Formulas Meet or Exceed cGMP Quality Standards. This product is manufactured in the United States in a FDA inspected and NSF / GMP certified facility.

Quatrefolic® is a registered trademark of Gnosis SPA Corp. Produced under US patent 7,947,662.

4.7
Rated 4.7 out of 5 stars
Based on 143 reviews
Total 5 star reviews: 120 Total 4 star reviews: 16 Total 3 star reviews: 3 Total 2 star reviews: 1 Total 1 star reviews: 3
95%would recommend this product
Customer-uploaded media carousel. Press left and right arrows to navigate. Press space or enter to open more details.
Slide 1 selected
Powered by OkendoOpen Okendo Reviews in a new window
143 reviews
  • LB Profile picture for Lynnette B.
    Lynnette B.
    I recommend this product
    Rated 5 out of 5 stars
    7 months ago
    Amazing!

    I have struggled with chronic fatigue since I can’t remember. I have been to the doctors and had test run to be told that I had some type of autoimmune issue but nothing concrete. Western medicine did not help and I felt helpless. I decided to look for a more natural way to help with my energy levels. So happy to find a supplement that is full of actual nutrients that my body needs, and can absorb!! Thank you Pure!!

  • A
    Amy
    I do not recommend this product
    Rated 1 out of 5 stars
    3 weeks ago
    1 Star

    Felt no difference

  • J
    Jeryd
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    5 Stars

    Energy levels are up, works extremely well.

  • RS
    R. S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    4 months ago
    By far the best MTHFR solution I've found

    Since being diagnosed with MTHRF, I've tried almost every methylated product available on Amazon. Most of them required me to take way too much folate and B12, too often, or too many products (TMG, NAC, etc.) in combination. This formula combines them all in a good ratio, and is designed to allow you to take 2 different types of folate (one that enters your bloodstream immediately, and one that follows after), so it lasts longer in your system at a lower dose. With this product, I only have to take half the recommended dose of folate and B12 (both 15 mg per day) and I don't have to pay extra to buy TMG. Pure Therapro RX is truly my life saver. Thank you very much.

  • KZ
    Ken Zalecki Z.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    5 months ago
    Energy Booster

    I have been taking this product for about 10 years now and it is the best that I have found to combat the downsides of MTHFR gene mutation. I am 70 yrs old and have tons of energy every day. I take 1 capsule in the morning usually at breakfast time and 1 capsule at dinner time. I was taking an equivalent product from Xymogen but found this to be priced better.

Reviews LoadedReviews Added

Frequently Asked Questions

Ingredients
Riboflavin (as riboflavin 5'-phosphate sodium) 25 mg, Vitamin B6 (as pyridoxal 5'-phosphate) 15 mg, Folate [(1,700 mcg DFE as Calcium Folinate and 1,700 mcg DFE as (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)(Quatrefolic®)], Vitamin B12 (500 mcg adenosylcobalamin & 500 mcg methylcobalamin) 1000 mcg, TrimethylgIycine (TMG) 650 mg

Other Ingredients
DRcaps® Acid-Resistant Capsule (Vegetable Cellulose), Tricalcium Phosphate

DOES NOT CONTAIN
Fillers, wheat, gluten, yeast, soy protein, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or artificial preservatives.

**Storage:**
PLEASE NOTE - B vitamins are extremely hygroscopic (absorb moisture from the air). If the desiccant is removed from the bottle and/or the capsules are placed into a pill box / plastic bag, the capsules may start to degrade especially if you are in a hot or humid climate. We recommend storing the bottle or your pill box in the refrigerator during hot / humid months for optimal freshness.

All Pure TheraPro Rx Formulas Meet or Exceed cGMP Quality Standards. This product is manufactured in the USA in a FDA inspected, NSF and GMP-certified facility for guaranteed quality and potency.

Methyl B Complete™ Supports Metabolic Function & Energy

Methyl B Complete™ is a cutting-edge formula comprised of 5 key nutrients: Quatrefolic® Folate for maximum MTHFR support, trimethylglycine, a super-bioactive blend of Vitamin B12 (including patented MecobalActive® Methylcobalamin), as well as Vitamin B6 in its coenzyme form and the highest-quality Vitamin B2 (Riboflavin). This synergistic formula is responsible for supporting healthy homocysteine levels, vibrant energy production, optimal detoxification, a robust metabolism, and peak cognitive function. 

Clinically Effective Formula

MTHFR stands for Methylenetetrahydrofolate Reductase, a key enzyme important to many processes in your body. This enzyme is essential in absorbing certain nutrients and detoxifying cells, which is vital to your health. MTHFR is instrumental in the methylation process, which supports turning off or on certain metabolic pathways/end products. It is estimated that anywhere between 30-60% of the population has an MTHFR gene mutation or varient, which can prevent the processing of key vitamins like vitamin B12 and folate. These vitamins are needed to support healthy metabolism, energy release from food, detoxification, and nervous system function. Methyl B Complete™  contains pre-methylated for optimal absorption. 

Uncompromising Quality

Methyl B Complete™ is formulated with only the highest quality B Vitamins in their most desirable forms, suitable even for the millions of Americans with MTHFR and COMT mutations. At PureTheraPro Rx®, we utilized only the finest patented Quatrefolic® Folate, as well as other B vitamins in their co-enzyme and pre-methylated forms for optimal absorption and bioavailability.

Purity Is Our Priority

Pure TheraPro Rx® provides supplement solutions to ensure your body gets the micronutrients necessary to support total-body health and vitality. Pure TheraPro Rx® supplements do not contain any fillers such as rice flour, corn starch, or wood pulp fibers like cellulose. Our manufacturing facility adheres to strict NSF/cGMP (Current Good Manufacturing Practices) guidelines.

A comprehensive system

Many of our biological systems are simultaneously impacted by lifestyle, diet and supplementation. When you provide an optimized environment for nutrients, they will work synergistically, resulting in greater outcomes. We recommend several complementary products based on supporting clinical study data and customer feedback.