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Discover BioActive B12 Full-Spectrum

***Introducing our new and improved BioActive Vitamin B12™!

1) As of 9/12/2023, Pure Thera's newly reformulated BioActive B12 is a STRONGER daily dose (5 drops = 5,000mcg of Vitamin B12 daily).

2) Thanks to our sophisticated formulation utilizing organic vegetable glycerin, we were able to remove the natural potassium sorbate preservative from the formula.

3) While the glass bottle is now smaller and the total number of of servings has been reduced, because the formula is now stronger (5,000mcg) you pay a nearly identical amount per microgram of B12. 

Please keep in mind when comparing our practitioner-recommended formulas to competitors’ that, here at Pure TheraPro, we are a China-free supplement brand. This means that we must go to great lengths and expense to source quality ingredients from reputable suppliers outside of China. Purity is our priority.

BioActive B12 "Full Spectrum" - is a high-quality VEGAN Vitamin B12 complex utilizing the three most important bioavailable forms of B12.

This advanced formula includes highly desirable ingredient forms that do not require conversion in the liver in order to be available for use by your cells.

  • METHYLCOBALAMIN -- Biologically Active Form: Utilizing third-party-tested Methylcobalamin with exceptional purity, our Methylcobalamin is an active, pre-methylated form of Vitamin B12 that is immediately able to be used by your body's cells and does not require extra work by vital methyl donors or your liver to be made bioavailable.

  • ADENOSYLCOBALAMIN -- Mitochondrial Form: An active "coenzyme" form of B12 and is utilized directly in B12-dependent enzyme reactions in the body.

  • HYDROXOCOBALAMIN -- Protector Form: Readily converts to Methylcobalamin and has a unique role in supporting detoxification processes.

  • From your blood cells to your nerves and down to your DNA, Vitamin B12 is a critical vitamin for the health of your body.

    We've carefully formulated this highly bioavailable, vegan BioActive B12 to include ALL 3 bioavailable forms of B12. Bioactive simply means that the precious B12 has already been converted into a form that your body can utilize immediately. 

    With these specialized bioactive forms, the B12 does not need to be converted in order to be available for use by your cells (conversion can be especially problematic for people with MTHFR issues such as MTR, MTRR, COMT as well as other gene defects and mutations).

    Did you know that both vegan and non-vegan individuals commonly suffer from B12 insufficiency? If you’re omnivorous, you may get some B12 from meats, dairy and eggs (often not nearly enough as we no longer consume organ meats); however vegetarians and vegans have a much more difficult time.

    If you’re a strict vegan, studies have confirmed that you’re likely to be insufficient in B12, unless you’re supplementing regularly. While rates of B12 insufficiency are much higher in vegetarians and vegans than in omnivores, that doesn’t mean it’s rare in omnivores. Approximately 1 in 20 omnivores are B12 insufficient. 

    B12 deficiency is also more common in people with gut problems because that often decreases intestinal absorption (including taking OTC drugs which block stomach acid).

    Older adults are also at risk as stomach acid levels decline as we age, which makes it difficult to cleave the Vitamin B12 from its protein bound form in food.

    The consequences of Vitamin B12 insufficiency are extremely serious and sometimes irreversible (nerve damage for example).

    Vitamin B12 is water soluble - our bodies are unable to store it for very long. Ultimately, it's very important that you are getting enough B12 in your diet every day - and the easiest, most bio-available method is to take this supplement consistently.

    Methylcobalamin - Assists methylation, supports brain & nerve health, circulatory & immune systems, and normal homocysteine levels.

    Adenosylcobalamin - Supports muscle recovery, mitochondrial structure and function, as well as the structure and function of the delicate myelin sheath.

    Hydroxocobalamin is a precursor form of Vitamin B12 converted in the body to both Methylcobalamin and Adenosylcobalamin. This form of B12 helps support mood, an overall sense of well being, energy production, clear thinking and detoxification.

    Manufactured in the USA in an NSF and GMP-certified facility, for guaranteed quality and potency. This supplement is lab tested to ensure the highest quality, potency and purity of each batch.

    Rated 4.6 out of 5 stars
    Based on 132 reviews
    Total 5 star reviews: 99 Total 4 star reviews: 18 Total 3 star reviews: 7 Total 2 star reviews: 6 Total 1 star reviews: 2
    89%would recommend this product
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    132 reviews
    • JG
      James G.
      Verified Buyer
      I recommend this product
      Rated 5 out of 5 stars
      My favorite b12 drops

      These have the three forms that the best doctors recommend (and NO cyannocobalamin!). They taste good, and they actually WORK! Just don’t get any on your shirt!

    • S
      I recommend this product
      Rated 5 out of 5 stars
      4 months ago
      5 Stars

      Worked great. within 1 1/4 bottles, brought my levels up to a range that was acceptable. Happy with the outcome!

    • J
      I recommend this product
      Rated 5 out of 5 stars
      4 months ago
      5 Stars

      Good flavor. Simple to use. quick and in nice condition delivery

    • PG
      Pratibha G.
      I do not recommend this product
      Rated 2 out of 5 stars
      4 months ago
      2 Stars

      Not sure about the quality but the dropper was clogged with what seems like dried liquid from the bottle

    • A
      I recommend this product
      Rated 5 out of 5 stars
      4 months ago
      5 Stars

      Purchased drops due to a bad pill reaction. I'm unsure about absorption; I won't know if it's working until my bloodwork is completed. Otherwise, I don't mind it.

    Reviews LoadedReviews Added

    Frequently Asked Questions

    Vitamin B12 as MecobalActive® Methylcobalamin, Adenosylcobalmin & Hydroxocobalamin

    Other Ingredients
    Triple-Distilled Water, USDA Certified Organic Kosher Vegetable Glycerin, Natural Potassium Sorbate Derived from Mountain Ash Tree Berries, Natural Citric Acid Derived from Citrus Fruits

    Fillers, wheat, gluten, yeast, soy protein, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or artificial preservatives.

    All Pure TheraPro Rx Formulas Meet or Exceed cGMP Quality Standards. This product is manufactured in the USA in a FDA inspected, NSF and GMP-certified facility for guaranteed quality and potency.

    BioActive B12 Supports Nervous System and Brain Health

    BioActive B12 is a high quality vegan B12 complex utilizing three bioavailable forms of this key vitamin. These forms require no conversion in the liver in order to be used by your cells. As a pure and potent supplement, BioActive B12 provides maximum absorption with a mild taste that is easy on the palate.  

    Clinically Effective Formula

    Vitamin B12 is a critical vitamin for the health of our bodies. We’ve carefully formulated this highly bioavailable Vegan BioActive B12 to include all three forms of B12, including methylcobalamin, adenosylcobalamin, and hydroxocobalamin. BioActive means that B12 has already been converted into a form that your body can utilize immediately. With these specialized bioactie forms, the B12 does not need to be converted in order to be available for use by your cells. 

    Uncompromising Quality

    Watch out! Most Vitamin B12 supplements contain cheap and ineffective Chinese cyanocobalamin. This undesirable form is not easily used by your body and must be converted in the liver via methylation; a serious problem for the millions of Americans with MTHFR mutations. And because it is derived from coal tar, it is also often tainted with unwanted toxins that can harm your body. Pure Thera’s BioActive B12 is formulated with the three best forms of Vitamin B12 in the world, and these forms are easily absorbed and utilized by your body and brain.

    Purity Is Our Priority

    Pure Thera provides supplement solutions to ensure your body gets the micronutrients necessary to support total-body health and vitality. Pure TheraPro supplements do not contain any fillers such as rice flour, corn starch, or wood pulp fibers like cellulose. Our manufacturing facility adheres to strict NSF/cGMP (Current Good Manufacturing Practices) guidelines.

    A comprehensive system

    Many of our biological systems are simultaneously impacted by lifestyle, diet and supplementation. When you provide an optimized environment for nutrients, they will work synergistically, resulting in greater outcomes. We recommend several complementary products based on supporting clinical study data and customer feedback.