The Root Cause of Your Cardiovascular Disease?

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The Pure TheraPro Team

The Pure TheraPro Education Team is comprised of researchers from diverse backgrounds including nutrition, functional medicine, fitness, supplement formulation & food science. All articles have been reviewed for content, accuracy, and compliance by a holistic integrative nutritionist certified by an accredited institution.
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Are your gums swollen, red and bleeding when you brush your teeth? This might be a sign of gingivitis which is the precursor of periodontal disease.

According to the CDC, over 47% of adults have periodontal disease. In the senior population, the rates are astronomical with over 70% of adults 65 and over having periodontal disease.

The issue is that mouth issues don’t just affect your mouth--they impact your overall health, including your heart. Inflammation around the tooth means that bacteria has been lurking long enough to build plaque and turn into calculus. This buildup extends below the gum line and develops colonies of bacteria which can then infiltrate the bloodstream.


Once in the bloodstream, the bacteria can inflame blood vessels and cause damage. Oral bacteria has been found within atherosclerotic vessels far from the mouth, supporting this. It is believed that the bacteria itself is not the initial root cause of cardiovascular issues resulting from mouth issues, but rather the inflammatory response that cascades as a result of the bacteria. This vascular damage due to inflammation can impact multiple organs, including the heart and brain. 

Atherosclerosis, then, is related to periodontal disease and can be extremely serious, causing cardiovascular blockage, circulatory issues, systemic inflammation and heart attack, even death. Inflammation around the heart as a result of infection, which is called endocarditis, is also a possible outcome. 

A study published in the AHA journal Hypertension also found that gum disease negatively impacts blood pressure, which is associated with inflammation, heart valve issues and blockage. 


This information gets even more scary when you look at studies on other effects of periodontal disease on the body. A 2018 study, for example, linked mouth bacteria and periodontal disease with rheumatoid arthritis and  pancreatic cancer risk.  As you can see, the connection between poor oral health and overall health may not be limited to just cardiovascular disease. 

If you’re wondering if you have periodontal disease, some warning signs include chronic bad breath, swollen gums that bleed when you brush or floss, sensitive gums when you chew, loose teeth, receding gums with sensitive teeth, painful teeth/gums, and change in your bite. 

Lifestyle choices and other disease states may also play a role in increasing risk. If you smoke, practice poor oral hygiene, have diabetes and immunodeficiencies, chronic stress, hormonal fluctuations, medications that cause dry mouth, such as antidepressants, or have cracked fillings, your risk factors for periodontal disease increase. 

Practicing good oral hygiene is one way to help reduce this risk. This includes brushing and flossing as well as avoiding processed, sugary foods that promote tooth decay. Supplements that help support the bones and teeth, such as vitamin D3, K2, magnesium and boron should be part of a daily regimen. 

Because several studies have shown the connection between periodontal disease and the stimulation of a systemic immune response as a result of oxidative stress, reducing reactive oxygen species (ROS) is imperative. This is why CoQ10 may also be an effective supplement in managing gum inflammation associated with periodontal disease. 

CoQ10 has powerful antioxidant properties. Low levels of CoQ10 have been associated with periodontitis. These studies have shown that supplementation with CoQ10 in conjunction with scaling and root planing helped reduce gum inflammation and prevent the progression of periodontitis compared with scaling and root planing on its own. 

With 24-hour sustained release, our MicroActive CoQ10 Enhanced with Micro PQQ +Shilajit, is uniformly absorbed--3x greater than crystalline CoQ10 and 2x more than solubilized CoQ10 because blood levels remain high for a longer period of time compared to regular CoQ10.  In an efficacy comparison study, 5 subjects participated in a 24-hour crossover design with a single dose of 180 mg of CoQ10. The results indicate that the bioavailability of the CoQ10 complex was significantly better than the crystalline form by a Factor of 3.7 (370%).

Each CoQ10 molecule is also complexed with beta-cyclodextrin, a natural compound made from potato starch that increases the solubility of CoQ10. Its easy transport through the digestive system further enables bioavailability directly to cells. Moreover, its absorption is not dependent on the presence of fat. Because of this superiority in absorption, our MicroActive CoQ10 is able to double lab values from baseline in 100% of users within three weeks, according to data.  

The addition of MicroPQQ provides enhanced protection to nerve cells, improvement of cognitive function, and relief from stress and insomnia, with 2.2 times better absorption than standard PQQ formulations, due to the 9+ hour sustained release profile. The combined ingredients and dose in this supplement have been clinically-studied with results showing improvement in short-term memory, focus and cognitive health superior to either ingredient alone.

PrimaVie® is an organic, purified shilajit from the Himalayan mountains, rich in fulvic acid to maximize your body’s absorption of CoQ10 & PQQ. PrimaVie shilajit is a nutrient that has been shown to double levels of CoQ10 in mitochondria. Combining CoQ10 and shilajit produced a 56% increase in energy production in the brain—40% better than CoQ10 alone. In muscle cells, there was a 144% increase in energy production (ATP)—27% better than CoQ10 alone.

This ideal anti-aging ingredient has many health benefits: Supports male sexual health, Mitochondrial energy booster, increases exercise endurance and overall fitness level, up-regulates steroidogenic genes (Patent Pending), up-regulates genes for collagen synthesis (Patent Pending) and improves the bioavailability of CoQ10.