Vitamin A and the Fat-Soluble Vitamin Balancing Act

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The Pure TheraPro Team

The Pure TheraPro Education Team is comprised of researchers from diverse backgrounds including nutrition, functional medicine, fitness, supplement formulation & food science. All articles have been reviewed for content, accuracy, and compliance by a holistic integrative nutritionist certified by an accredited institution.
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Fat soluble vitamins (A, D, E and K)  work together to create balance in your system. How well vitamin E is absorbed and utilized, for example, depends on the other fat-soluble vitamins and vice versa. Vitamins A, D, E and K have an important synergistic relationship. They are also vital in ensuring proper absorption and bioavailability of calcium from the foods we eat.

Vitamin A, for example, works with vitamin D to support your immune system and bone and teeth health. In addition, vitamin A is an important antioxidant that may improve vision and skin.

Studies have demonstrated this checks and balances system that exists between vitamin A and vitamin D in that vitamin A also reduces D toxicity levels and vice versa. This goes for all fat-soluble vitamins.  

Fat soluble vitamins, therefore, work like hormones in our system. One is linked strongly with the other. In lab rats given 10 times the normal amount of Vitamin A, for example, blood levels of vitamin E and D dropped, as a result. When given 50 times the normal amount, their vitamin K levels also decreased. The findings suggest that vitamin A and E toxicity may be due to a vitamin K deficiency, being that rats began to experience internal hemorrhaging as their vitamin K levels dropped. 

When you’re reviewing your diet and supplement protocol, make sure you’re getting a balanced amount of these crucial vitamins daily.Vitamin D-rich foods include fatty fish, mushrooms and egg yolks. Foods rich in vitamin K include green things—kale, spinach, turnip greens, Brussels sprout, broccoli and asparagus. Vitamin E is found in nuts, seeds, sunflower and olive oil.

If you’re looking to supplement your diet with foods high in vitamin A, reach for nutrients that are yellow and orange, such as cantaloupe, squash, sweet potatoes and carrots.  Some leafy green vegetables also contain vitamin A as well as red spices, such as red and cayenne pepper and paprika.

Remember that Vitamin A’s benefits are enhanced when they are kept in balance by the other fat-soluble vitamins.

Here are some of Vitamin A’s benefits:

Eye Health:

Vitamin A slows the progression of vision loss as a result of the normal aging process. A study showed that supplementing with optimal levels of vitamin A reduced their development of macular degeneration by 25%. 


You’ve likely heard of Retin-A, which is a topical prescription of vitamin A proven to reduce wrinkles, acne and age spots. Ingesting vitamin A helps ward off free radicals that reduce skin collagen levels. Collagen promotes youthful, plump and tight skin. Free radicals, over time, can create damage that accelerates aging, resulting in sagging skin, wrinkles, a blotchy complexion and age spots. 

Supports Immune Function:

Your lymphatic system in responsible for removing bacteria, pathogens, parasites, viruses and other toxins from your system. It absorbs fats and fat-soluble vitamins from the digestive system and transports these into the bloodstream where it moves through your lymphatic system. Retinol is absorbed from the gut, converted to retinyl palmitate in the intestinal mucosa, then transported and stored as retinyl palmitate in the liver.

Vitamin A helps your body to produce white bloods cells that fight infection and cleanse the blood to support the lymphatic system. Studies have demonstrated that Vitamin A has positive effects on various respiratory diseases, such as pneumonia and measles as well as digestive diseases and hand, foot and mouth disease.

In fact, the World Health Organization (WHO) and American Academy of Pediatrics recommend administering 200,000 IU of vitamin A immediately to children older than one years if diagnosed with measles and a second dose of 100,000 IU the next day: “Vitamin A deficiency may be a large factor in determining the outcome of measles. . . .When a child with marginal stores of vitamin A gets measles, the available vitamin A is quickly depleted, presumably reducing the ability to resist secondary infections or other consequences. This would exacerbate the already reduce immunocompetence thought to be associated with measles infection.” 

Our Vegan ADK is the first of its kind vegan full spectrum supplement that provides you with balance, purity and 5-in-1 support: Vitamin A in two forms, D3 and K2 as MK-7 and MK4. This formulation promotes immune function, healthy skin and eyes, strong bones and arteries as well as support for your heart, kidney and cognitive health.

Micellized vitamin A is highly bioavailable and contains 2 forms, Palmitate, the active form and Beta-carotene, the precurser form. Being “micellized” allows for greater bioavailability and absorption in the bloodstream.


This formulation contains our Pureshine, wild lichen-sourced D3 along with K2 (MK-7 and MK-4) derived from chickpea fermentation and extracted Gerinol through the cleanest, purest form, Co2 extraction.

Just 5 drops (like a raindrop) on your tongue each day provides you with over 1500 mcg of vitamin A, 5000 IU vitamin D and 680 mcg K2. Absorption of fat-soluble vitamins is increased when you take these vitamins at the same time as eating a meal that contains healthy fat.